Temperature Dependent Release of Cyanide from Sodium Nitroprusside
نویسندگان
چکیده
منابع مشابه
In vivo release of cyanide from sodium nitroprusside.
Brain cytochrome oxidase activity was measured after the in vitro addition of potassium cyanide (KCN) or sodium nitroprusside (SNP). Activity of cytochrome oxidase was sensitive to KCN; however, this activity was unaffected by SNP. In SNP- and KCN-treated animals brain cytochrome oxidase activities were measured. At 3 min after SNP injection, inhibition of the enzymatic activity was the same as...
متن کاملCyanide and thiocyanate concentrations following sodium nitroprusside infusion in man.
Twenty-six patients, receiving an infusion of sodium nitroprusside (SNP) during surgery, had considerable increases in both red cell and plasma cyanide concentration, but only small changes in plasma thiocyanate concentration. There was a linear relationship between both plasma and RBC cyanide concentrations and the total dose of SNP. The expired cyanide concentration followed the changes in th...
متن کاملNitroprusside and cyanide.
Sir,—An otherwise excellent and thorough report by Vesey, Cole and Simpson (1976) fails to acknowledge or refute a hypothesis which has already appeared in this Journal (Smith and Kruszyna, 1976a) about the mechanism by which cyanide is released from nitroprusside in vivo, and the significance of that reaction for blood cyanide concentrations. We are delighted with the confirmation that "The re...
متن کاملTemperature-dependent model of human cardiac sodium channel
Cardiac sodium channels are integral membrane proteins whose structure is not known at atomic level yet and their molecular kinetics is still being studied through mathematical modeling. This study has focused on adapting an existing model of cardiac Na channel to analyze molecular kinetics of channels at 9-37°C. Irvine et al developed a Markov model for Na channel using Neuronal Network Model ...
متن کاملTemperature-dependent model of human cardiac sodium channel
Cardiac sodium channels are integral membrane proteins whose structure is not known at atomic level yet and their molecular kinetics is still being studied through mathematical modeling. This study has focused on adapting an existing model of cardiac Na channel to analyze molecular kinetics of channels at 9-37°C. Irvine et al developed a Markov model for Na channel using Neuronal Network Model ...
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ژورنال
عنوان ژورنال: Journal of UOEH
سال: 1983
ISSN: 0387-821X,2187-2864
DOI: 10.7888/juoeh.5.201